Sublocade: The Much in Demand OPD Treatment

Sublocade, a revolutionary monthly treatment of OPD, aids in preventing opioid as well as its relapse in patients who are clinically addicted and dependent on opioids. Sublocade cost is pretty low and thus is preferred by many.

A general introduction

Sublocade treatment is a revolutionary treatment that is used for opioid use disorder. This is a monthly injection. It can aid in preventing opioid relapse as well for patients who are clinically addicted and are dependent on opioids. Being the first treatment of its kind to be approved by the FDA, it has displayed extremely promising reports for being a maintenance therapy for opioid dependence.

What is this treatment and medicine

It is an injection generally administered once in a month of buprenorphine which has been successfully used for treating opioid use disorder of late. Sublocade got its FDA approval on November 30, 2017 for use by patientsof opioid use disorder. These people are already under the treatment with a form of buprenorphine like Suboxone, Subutex or Zubsolv which is absorbed with the help of the tissue in the mouth. A minimum treatment of seven days should be completed and tapered their dosages to manage their symptoms. Sublocade price is very affordable causing it to be in demand by the most.

How Sublocadehelps Opioid Addiction

Buprenorphine is the chief ingredient that Sublocade is composed of. Being a partial opioid receptor agonist, Buprenorphine binds to the same receptors as opioids and activates them to give a euphoric or other worldly effect which is very similar to opioid drugs. Buprenorphine lasts much longer than many other illicit opioid drugs. However it does not give as extreme euphoric sensation and has much less grave side effects.

Itassists to relieve the withdrawal symptoms of opioid dependence.It also aids to stop completely or avert cravings withoutmaking the user high. Unlike many medications which contain buprenorphine that are used to heal opioid addiction and orally administered by sublocade treatment doctor, it does not contain naloxone. An opioid receptor inhibitor, Naloxone was added to buprenorphine in order to increase the safety of the medication and aid in the prevention of abuse.


A study in comparison: Sublocade vs. Vivitrol

Both used as maintenance therapies for opioid use which is largely called OPD disorders, Sublocade and Vivitrol, vary in their mechanism of action.

Vivitrol: it is an injectable form of naloxone. It is an opioid receptor inhibitor. Vivitrol functions by stopping opioids from binding to the receptors that blocks any high or sense of euphoria. Thus, a person consuming Vivitrol would not be getting the high that they normally would if they were using opioids. This makes opioid use extremely undesirable. It also helps individuals with opioid dependence to avoid relapse when they stopusing opioids.

Sublocade: It is an injectable form of buprenorphine. It also acts by binding to opioid receptors. However it stimulates the receptors and doesn’t inhibitthem. Sublocade would also block the additional effect of opioids. Butit has been reported of having slight euphoric effect itself. This medicine also reduces the withdrawal symptoms as well asworks to prevent cravings for opioids. It is an effective maintenance therapy used in multiple sublocade treatment centers.

Contraindications and Risksinvolved in this treatment

Although sublocade cost is pretty low and thus it is preferred by many, few things shall be kept in mind before this treatment.

  • People who have hypersensitivity or are allergic to buprenorphine should not be administered with sublocade.
  • It shall be kept in mind that It should also not be used in combination with other types of drugs.
  • It is always a best idea to first speak to a physician before using it in combination with any other drug.
  • It must be kept in mind that Sublocade should never be used as anintravenous injection. Although a liquid, when it is injected, becomes solid when it enters the body. If this drug enters the blood, it runs a high risk of causing major clotting issues. It cans evenprove fatal.
  • It should never be administered into the muscle as well. It is meant for onlysubcutaneous usage.
  • Similar to other buprenorphine-containing medicine, Sublocade, runs a high risk of causing ineffective as well as slow breathing or sometimes slowing of neurological functions which can be life-threatening. Sublocade should be immediately discontinued if a patient has symptoms of either of these two conditions.
Sublocade Treatment

Sublocade Treatment: Buprenorphine Abuse and Other Side Effects

Buprenorphine: Abuse, Misuse and Addiction

Buprenorphine in Sublocade has a track record of exposing it’s patients and other users to the risks of opioid addiction, abuse as well as misuse. It can lead to multiple severe hazards like overdose and even death. A sublocade treatment doctor should understand each patient’s risk beforehand in order to prescribe buprenorphine. He or she must also monitor all the patients regularly for the development of these conditions and behaviours. Opioid Analgesic Risk Evaluation and Mitigation Strategy or REMCare used to make sure that the benefits of opioid analgesics would outweigh the risks of abuse addiction and misuse. The Food and Drug Administration more commonly known as FDA has required a REMS for these products. Under all the requirements of the REMS, these drug companies with approved opioid analgesic products must arrange education programs that are REMS-compliant which will be available to healthcare providers.

All the healthcare providers in the sublocade treatment centers are strongly encouraged to do these following things:

  • Completion of a REMS-compliant education program
  • Make the patients and/or their caregivers understand and counsel with every prescription, serious risks, on safe use disposal and storage of these products
  • Emphasize the patients and/or their caregivers the significance of reading the Medication Guide each time it is provided by their pharmacists
  • Consideration of other tools in order to improve the patient, their household and alsotheir community safety.

Cause of Life-Threatening Respiratory Depression

Fatal, life-threatening and serious respiratory depression might occur due to the use of buprenorphine. Monitoring the respiratory depression, more specifically during the time of initiation of buprenorphine or following a dose increase must be done. Abuse or even misuse of buprenorphine by swallowing, chewing, or injecting and snoring buprenorphine extracted from the buckle film might cause the uncontrolled delivery of buprenorphine. It might also pose a significant risk of overdose and finally, death.

Accidental Exposure

It is to be kept in mind that any kind of accidental exposure of even one single dose of buprenorphine, especially by any child can result in a fatal case of overdose.

Neonatal Opioid Withdrawal Syndrome

Prolonged usage of buprenorphine while one is pregnant might cause neonatal opioid withdrawal syndrome. It may be life-threatening in case it is not recognized as well as treated immediately and properly. It also needs to be well managed in accordance to the protocols that are developed by neonatology experts.

If opioid use is needed for a lengthy period of time in a pregnant woman, it is advisable that the patient be enlightened about the risk of neonatal opioid withdrawal syndrome. The assurance that appropriate treatment will be available shall be given.

Sublocade Treatment

Risks from Concomitant Use in Benzodiazepines or Other similar CNS Depressants

Reserving concomitant prescribing of buprenorphine and benzodiazepines or other CNS depressants for use in patients to whom any kind of alternative treatment options are inadequate is important. Limiting the dosages and its durations to the minimum is also needed. It can only be said that any sublocade treatment is apt when the symptoms and sign of respiratory depression as well as sedationis properly checked.

The Side effects that would require immediate medical attention

In addition to all the desired effects, buprenorphine, which is an active ingredient contained in Sublocade may also cause some undesired after effects. Even though not all of these side effects may occur, if in case they do occur, they call for immediate medical attention.

One should inform the doctor immediately if any of the following side effects occur while the intake of buprenorphine:

  • Bloating or swelling of the arms, face, lower legs, hands or feet.
  • Bladder pain
  • Blurred vision
  • Bloody or cloudy urine
  • Diarrhoea
  • Cough producing mucus
  • Difficulty in breathing
  • Difficult, painful or burning urination
  • Dizziness
  • Fever
  • Frequent urge to urinate
  • Lower back pain
  • Side pain
  • Nausea
  • Loss of appetite
  • Pale skin
  • Mouth or throat pain
  • Rapid weight gain
  • Nervousness
  • Stomach pain
  • Pounding in the ears
  • Slow or fast heartbeat
  • Tightness in the chest
  • Unusual bleeding or bruising
  • Tingling of the hands or feet
  • Unusual weight loss
  • Unusual tiredness
  • Troubled breathing with exertion

Since Sublocade price is very low, people tend to use this more and more these days. However proper precaution should be taken.

Finding The Perfect Buprenorphine Treatment Provider For You

Finding The Perfect Buprenorphine Treatment Provider For You

Sublocade or the extended-release burprenorphine which is also known as BXR has seen a massive growth indemand for the treatment of opiate use disorder or OUD in recent times. It has being tested positive for Highly Potent Synthetic Opioids or HPSO for all the opioid users.

Adults with moderate or severe OPD are inducted and clinically stabilized of sublingual buprenorphine or naloxone, BUP-ER injections. They are given generally monthly doses. These injections are administered subcutaneously. More cases of success are being reported of this by sublocade treatment doctor. They have reported a high percentage of abstinence in their patients. These reports have been mainly concluded with a combination of percentage urine samples marked negative for opioids and also, negative self-reports for illicit opioid use at the end of a certain period oftime.

Sublocade cost is very cheap, enabling almost everyone to be able to use it. Moreover they are easy to use.

The sublocade doctors near me are all qualified per the Drug Addiction Treatment Act of 2000 or DATA 2000 and the Comprehensive Addiction and Recovery Act of 2016 or CARA to treat opioid dependence among the patients.

Most Important Information About Sublocade

There have been many reported cases of the serious damage in patients due to the improper administration of sublocade near me. The risk of possible harm or death from self-injecting sublocade into a vein or intravenously has led the health standard organisations to implant a restricted program on sublocade usage.

The Restrictions Are As Follows

  • Sublocade price is cheap. However it is unavailable in retail pharmacies. Thus one cannot just walk into a retail pharmacy and ask for a sublocade dose.
  • The sublocade injections must be only accessed and administered by a properly experienced as well as certified health care provider.
  • During a medical emergency the patient or the family of the patient who is already being treated with sublocade should inform the emergency medical staff that they are physically dependent on opioid.
  • Buprenorphine, the medicine which is in sublocade, might cause life-threatening and serious health risks. This might happen especially if one is taking or using certain other drugs or medicines.

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The Multiplehealth Hazards

One shouldimmediately call the healthcare provider or get emergency help if any of these discomforts occur:

  • If one feelsany kind of faintness ordizziness
  • If they are having slower breathing than they usually have
  • Feel severely drowsy
  • Complain of having high body temperature
  • If they develop problems with body coordination
  • If their speech gets affected like it becomes slurry
  • In case they complain of having any mental changes like confusion or disconnection to the reality
  • If they are unable to think well or with clarity
  • If they feel any kind of agitation
  • Complain of having high body temperature
  • If their musclesstiffen
  • Incase they have trouble in walking
  • If they report about slowed reflexes

All of these can be signs of an overdose. They can be also an indication ofother serious problem and thus should not be overlooked at any given point of time.

If overlooked, death or other consequential damages could happen including life threatening breathing problems. The following list tells us of the medicines that might cause these kinds of hazards.

  • Anxiety medicines or benzodiazepines
  • Sleeping pills
  • Tranquilizers
  • Muscle relaxants
  • Sedatives
  • Antidepressants
  • Antihistamines
  • Or they have consumed alcohol during treatment with sublocade.

One must inform thehealthcare providers prior hand if they are taking any of these medicines and they drink alcohol.

It shall be kept in mind that sublocate is a controlled substance orCIII since it contains buprenorphine.

Buprenorphine can be a target for those people who abuse street drugs or prescription medicines.

There have been reported cases of death in those who are not opioid dependent and have who received buprenorphine sublingually.

Another important information one must keep in mind is that one must not use sublocade if they are allergic to buprenorphine or any kind of ingredients in the prefilled syringe like the Atrigel Delivery System. It is a biocompatible solventN-methyl-2-pyrrolidone or widely known as NMP and biodegradable poly (DL-lactide-co-glycolide) polymer.